Nephrotic vs Nephritic Syndrome: Key Differences
Nephrotic Syndrome is caused by increased glomerular permeability, resulting in heavy proteinuria (>3.5 g/day), hypoalbuminemia, generalized edema, hyperlipidemia, and lipiduria. Common causes include minimal change disease, FSGS, membranous nephropathy, diabetic nephropathy, amyloidosis, and lupus nephritis.
Nephritic Syndrome results from glomerular inflammation and is characterized by hematuria with RBC casts, hypertension, oliguria, azotemia, and mild-to-moderate proteinuria. Common causes include post-streptococcal glomerulonephritis, IgA nephropathy, rapidly progressive glomerulonephritis, and lupus nephritis.